Fluid Therapy Adherence Monitoring for Patients Following Physician Prescribed Protocols

Real-world hydration data for care teams, health systems, and pharma patient support programs

DID YOU KNOW ?
Dehydration is one of the top 10 causes of hospitalizations in adults over 65.

Clinical Evidence for Fluid Therapy Adherence Monitoring

2.5x higher risk of chronic kidney disease

Among individuals with the lowest daily water intake 👈

~50% reduction in UTI recurrence

With increased daily fluid intake in women with recurrent cystitis 👈

~60% of kidney stone patients forget to drink

As a barrier to meeting physician-prescribed fluid targets 👈

Self-reported fluid intake is clinically unreliable*

Patients underestimate how much or how little they they drink 👈 *Until now.

Water.io Care exists to ensure you stay on protocol with what your doctor is prescribing.
Water.io Care measures how much fluid you consume, compares it to your physician's prescribed target, and gives your care team the verified data they need to support your treatment.

For Pharma Partners: Real-World Longitudinal Patient Home Data

For many high-cost injectable medications, including platinum-based chemotherapy, urate-lowering therapies, and CKD agents, hydration is a critical but often overlooked component of the treatment protocol. Injection adherence and hydration compliance go hand in hand. One without the other leaves a gap in the patient picture.

PSP Tracks Today

* Did the patient inject? * When? * How often? Device-verified

WaterioCare Adds

* Did the patient hydrate? * How much? * When? Physician-prescribed target

Pharma Receives

* Complete adherence picture * Longitudinal RWE data * Supports adverse event reduction Stronger PSP ROI story

Turn Hydration Protocols 
Into Patient Outcomes
Water.io Care enables real-time hydration tracking for patients on high-risk injectable therapies—supporting adherence, reducing complications, and protecting drug performance beyond the clinic.

Injectable drug classes where hydration is clinically mandated

ONCOLOGY

Key injectables: Cisplatin, Carboplatin, Daratumumab-SC, Rituximab-SC, G-CSF agents (Neulasta/Zarxio), Leuprolide Hydration mandate: Labels require aggressive pre/post-infusion hydration to prevent nephrotoxicity — rarely monitored at home.

GOUT / URIC ACID

Key injectables: Krystexxa (pegloticase) ~$30K/series; Canakinumab (Ilaris) SC for acute flares Hydration mandate: Dehydration is the #1 trigger for breakthrough flares. At $30K/series, pharma has strong incentive to protect efficacy.

KIDNEY / CKD

Key injectables: Darbepoetin alfa (Aranesp), Epoetin alfa (Epogen), Feraheme IV iron, Parsabiv Hydration mandate: CKD patients require precise daily fluid targets. Water.io monitors against physician-prescribed goals.

TAKE ACTION NOW
DON'T WAIT ANY LONGER

Intellectual and Developmental Disabilities (IDD)

8.5 million people with IDD in the U.S.

Many rely on caregivers or support staff to follow daily health protocols — including physician-directed hydration. 👈

Up to 52% experience urinary incontinence

vs. 11% in the general population, with UTIs a major complication that adequate hydration can help prevent as part of a clinical care plan. 👈

Thirst cannot be reliably self-reported

Many individuals with IDD cannot perceive or communicate thirst, making caregiver-verified hydration tracking essential for safe medical care. 👈

Additional Supported Conditions

Chronic Kidney Disease  | Recurrent UTIs  |  IBS & IBD  |  Diabetes |  Post Surgical Recovery

The Problem
  • Patients are given specific fluid targets with no objective method to track them.
  • Self-reported intake is documented across clinical literature as consistently inaccurate.
  • Physicians have no visibility into real-world fluid behavior between appointments.
  • Caregivers managing high-risk patients lack any remote monitoring tool for hydration.
  • Non-adherence to fluid protocols drives preventable hospitalizations and acute episodes.
The Solution - Water.io Care  
Water.io Care is intended for individuals at risk of dehydration or fluid imbalance due to medical conditions and should be used under the direction of a healthcare professional.

  • Proprietary cap sensor measures fluid intake volume with every sip, objectively.
  • Eliminates self-reporting — timestamped intake records replace patient memory.
  • Real-time data accessible to caregivers and care teams via companion app.
  • Daily, weekly, and trend reporting supports documentation at follow-up appointments.
  • Physician-configured target-setting aligns each patient's goal with their prescribed protocol.

Prescribed Protocol

Physician-Directed

Fluid targets are set according to your doctor's prescription.

Objectively Verified

Every sip is measured and recorded. Adherence data replaces self-reporting, which clinical literature shows is consistently unreliable.

Clinically Shared

Intake records are accessible to your care team, enabling real-world monitoring between clinic visits and supporting informed treatment decisions.

Product Specifications

Dual Sensor Technology

Optical and IMU motion sensor measures every sip against a physician-prescribed daily fluid target.

Adherence Alerts

Visual and haptic notifications when patients fall outside their prescribed fluid targets.

Multi Language Support

English, French, Spanish, Russian, Hebrew, Arabic, and more languages to come.

Where Physicians Prescribe Specific Hydration Protocols
Across a range of chronic conditions, physicians prescribe specific daily fluid targets. Non-adherence is clinically significant and, until now, impossible to verify outside a clinical setting.
Physicians Can Prescribe. 
Adherence Can Now Be Verified.
Fluid intake instructions are among the most commonly issued — and least verifiable — clinical recommendations. Self-reported intake is well-documented to be unreliable. Water.io Care closes this gap.

Blog

  • Mar 10, 2026

Why Hydration Matters More for People Living With Diabetes

Hydration plays an important role in daily wellbeing for people living with diabetes. Learn why fluid balance matters and how simple reminders can help support better hydration habits.

Read More
  • Mar 1, 2026

Hydration and Chronic Kidney Disease: Why Consistent Fluid Intake Matters

Learn why consistent hydration plays an important role in daily kidney health management and how simple tools can help support steady fluid intake throughout the day.

Read More
Water.io Care
Physician-Directed Fluid Therapy Adherence Monitoring

Contact Us

  • 575 5th Avenue, Manhattan, New York, NY, United States
  • Clinical Inquiries & Provider Partnerships

Whether you are a clinician evaluating Water.io Care for a patient hydration program, a health system exploring integration, a pharma or life sciences partner interested in patient home data, or a researcher interested in fluid adherence technology — we welcome your inquiry.

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